• Dr. Paul Dhillon MB BCh CCFP



  1. List ONE reversal agent for reversing bleeding in a patient on Dabigatran.

  2. List THREE medications / management steps that can be used to stop bleeding in a patient on Warfarin.

(answers below)

Make it stop! Just make it stop!

Praxbind™ is way easier to remember the spelling for than Idarucizumab.

In cases of life-threatening, uncontrolled bleeding, or in patients who need emergent surgery, we can now reverse Dabigatran. Pretty quickly as well! 2.5g of Praxbind™ given twice for a total dose of 5g IV within 15 minutes. Now you know!

Conveniently, it was the same company that makes Pradaxa that came up with the antidote, at over $3000 dollars a pop.

DID YOU KNOW – WARFarin comes from the acronym from the Wisconsin Alumni Research Foundation and the ending indicates its link to coumARIN.

Reversing Warfarin can be done by:

1. Vitamin K and

2. Octaplex [Unactivated prothrombin complex concentrates (PCC)] or

3. Fresh Frozen Plasma

4. Dialysis

And don’t forget the simple stuff: STOP Warfarin/Pradaxa and direct pressure along with transfusion of blood products and fluids if required.

EXAM TIP - Using trade names vs generic. Either is acceptable on the exam according to the CFPC’s SAMPs Instructions to Candidate!

Reference List




REGISTRATION OPEN! The Review Course Winter 2017 is open now and selling fast!

See our registration page for more details and make sure you sign up before we sell out in 2017!

Highly Rated - Thousands of Attendees
  • Facebook
  • Twitter
  • Instagram

© The Review Course in Family Medicine Inc. | About Us | Privacy Policy

The only Canada-Wide CCFP exam course - created by two Family Doctors who wished this existed when we were residents, and are on a mission to help CCFP exam candidates. Disclosures: The Review Course founders have no conflicting commercial interests. As is the case with any private events hosted on a university campus or hospital, this event is not affiliated with nor endorsed by the host venues. Our materials are peer-reviewed and prepared by Canadian physicians; we do not guarantee that our preparation materials are representative of any Canadian examination and we do not provide questions from any other examination nor are they intended as medical advice. The College of Family Physicians of Canada does not affiliate with nor endorse any exam preparation course.